CNDAC hydrochloride

Names

[ Name ]:
CNDAC hydrochloride

[Synonym ]:
CNDAC hydrochloride
(2R,3S,4S,5R)-2-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-5-(hydroxymethyl)oxolane-3-carbonitrile hydrochloride
2'-Cyano-2'-deoxyarabinofuranosylcytosine

Biological Activity

[Description]:

CNDAC hydrochloride is a metabolite of the orally active agent sapacitabine, and a nucleoside analog[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Liu XJ, et al. Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks. Chin J Cancer. 2012 Aug;31(8):373-80.

Chemical & Physical Properties

[ Boiling Point ]:
596.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₃ClN₄O₄

[ Molecular Weight ]:
288.68800

[ Flash Point ]:
314.8ºC

[ Exact Mass ]:
288.06300

[ PSA ]:
135.38000

[ Vapour Pressure ]:
9.77E-17mmHg at 25°C

CNDAC hydrochloride

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds