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Dermaseptin

Names

[ CAS No. ]:
136033-70-0

[ Name ]:
Dermaseptin

[Synonym ]:
L-Alanyl-L-leucyl-L-tryptophyl-L-lysyl-L-threonyl-L-methionyl-L-leucyl-L-lysyl-L-lysyl-L-leucylglycyl-L-threonyl-L-methionyl-L-alanyl-L-leucyl-L-histidyl-L-alanylglycyl-L-lysyl-L-alanyl-L-alanyl-L-leu ;cylglycyl-L-alanyl-L-alanyl-L-alanyl-L-α-aspartyl-L-threonyl-L-isoleucyl-L-seryl-L-glutaminylglycyl-L-threonyl-L-glutamine
L-Glutamine, L-alanyl-L-leucyl-L-tryptophyl-L-lysyl-L-threonyl-L-methionyl-L-leucyl-L-lysyl-L-lysyl-L-leucylglycyl-L-threonyl-L-methionyl-L-alanyl-L-leucyl-L-histidyl-L-alanylglycyl-L-lysyl-L-alanyl-L ;-alanyl-L-leucylglycyl-L-alanyl-L-alanyl-L-alanyl-L-α-aspartyl-L-threonyl-L-isoleucyl-L-seryl-L-glutaminylglycyl-L-threonyl-

Biological Activity

[Description]:

Dermaseptin-S1 is an antimicrobial peptide derived from frog skin against filamentous fungi[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Mor A, et al. The vertebrate peptide antibiotics dermaseptins have overlapping structural features but target specific microorganisms. J Biol Chem. 1994 Dec 16;269(50):31635-41.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
2954.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C152H257N43O44S2

[ Molecular Weight ]:
3455.059

[ Flash Point ]:
1740.3±34.3 °C

[ Exact Mass ]:
3452.863525

[ LogP ]:
-4.49

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.565

Related Compounds