5’-(4,4’-Dimethoxytrityl)-5-methyluridine

Names

[ CAS No. ]:
138239-62-0

[ Name ]:
5’-(4,4’-Dimethoxytrityl)-5-methyluridine

[Synonym ]:
1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
1-(5-O-(bis(4-methoxyphenyl)phenylmethyl)-β-D-ribofuranosyl)-5-methyl-1-1H,3H-pyrimidine-2,4-dione
5'-O-(4,4'-dimethoxytrityl)-5-methyluridine
1-[5-O-(bis(4-methoxyphenyl)phenylmethyl)-β-D-ribofuranosyl]-5-methyl-1-1H,3H-pyrimidine-2,4-dione

Biological Activity

[Description]:

5’-(4,4’-Dimethoxytrityl)-5-methyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

Chemical & Physical Properties

[ Molecular Formula ]:
C31H32N2O8

[ Molecular Weight ]:
560.59

[ Exact Mass ]:
560.21600

[ PSA ]:
132.24000

[ LogP ]:
2.49010

Related Compounds