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(-)-4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid

Names

[ CAS No. ]:
13878-10-9

[ Name ]:
(-)-4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid

[Synonym ]:
Benzenepentanoic acid, γ-acetyl-2-chloro-γ-phenyl-
4-(2-Chlorobenzyl)-5-oxo-4-phenylhexanoic acid

Biological Activity

[Description]:

Caprochlorone has antiviral activity against orthopoxvirus. Caprochlorone can inhibit cell penetration by virus, also delays release of newly formed virus from the cell. Caprochlorone decreases the titers of influenza virus in infected-mice lungs[1][2][3].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[Target]

Orthopoxvirus, Influenza[2]


[References]

[1]. Smee DF, Sidwell RW. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003;57(1-2):41-52.

[2]. Stanfield FJ, Haff RF, Stewart RC. The antiviral activity of caprochlorone. Proc Soc Exp Biol Med. 1967;125(1):297-303.

[3]. LIU OC, et al. Studies on the chemotherapy of viral infections. II. The effect of caprochlorone on influenza virus infections in mice. J Immunol. 1957;78(3):222-227.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
477.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H19ClO3

[ Molecular Weight ]:
330.805

[ Flash Point ]:
242.6±28.7 °C

[ Exact Mass ]:
330.102264

[ LogP ]:
3.87

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.577

Related Compounds