α-Cytidine

Names

[ Name ]:
α-Cytidine

[Synonym ]:
α-Cytidin
4-Amino-1-((2S,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one
1-(α-D-ribofuranosyl)-4-aminopyrimidin-2-one
4-amino-1-α-D-ribofuranosyl-1H-pyrimidin-2-one

Biological Activity

[Description]:

α-Cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₃N₃O₅

[ Molecular Weight ]:
243.22

[ Exact Mass ]:
243.08600

[ PSA ]:
130.83000