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MBX2329

Names

[ CAS No. ]:
1438272-42-4

[ Name ]:
MBX2329

[Synonym ]:
1-[2-(2-Ethylphenoxy)ethyl]azepane hydrochloride (1:1)
1H-Azepine, 1-[2-(2-ethylphenoxy)ethyl]hexahydro-, hydrochloride (1:1)

Biological Activity

[Description]:

MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[References]

[1]. Basu A, et al. New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion. J Virol. 2014;88(3):1447-1460.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H26ClNO

[ Molecular Weight ]:
283.837

[ Exact Mass ]:
283.170288

[ Storage condition ]:
2-8°C

Related Compounds