N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine

Names

[ Name ]:
N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine

Biological Activity

[Description]:

N6-Benzoyl-2'-fluoro-2'-deoxyarabinoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₆FN₅O₄

[ Molecular Weight ]:
373.34

[ Exact Mass ]:
373.11900

[ PSA ]:
122.39000

[ LogP ]:
0.74030