CCT245737
Names
[ CAS No. ]:
1489389-18-5
[ Name ]:
CCT245737
[Synonym ]:
2-Pyrazinecarbonitrile, 5-[[4-[[(2R)-2-morpholinylmethyl]amino]-5-(trifluoromethyl)-2-pyridinyl]amino]-
5-{[4-{[(2R)-2-Morpholinylmethyl]amino}-5-(trifluoromethyl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile
5-{[4-{[(2R)-2-Morpholinylmethyl]amino}-5-(trifluormethyl)-2-pyridinyl]amino}-2-pyrazincarbonitril
5-{[4-{[(2R)-2-Morpholinylméthyl]amino}-5-(trifluorométhyl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile
CCT245737
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Chk1:1.3 nM (IC50)
Chk2:2440 nM (IC50)
ERK8:130 nM (IC50)
PKD1:298 nM (IC50)
RSK2:361 nM (IC50)
RSK1:362 nM (IC50)
FLT3:582 nM (IC50)
MARK3:698 nM (IC50)
NUAK1:711 nM (IC50)
CLK2:1370 nM (IC50)
BRSK1:1660 nM (IC50)
AMPK:2970 nM (IC50)
PHK:3470 nM (IC50)
CDK2/CyclA:3850 nM (IC50)
CDK1/CyclB:9030 nM (IC50)
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
547.2±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C16H16F3N7O
[ Molecular Weight ]:
379.340
[ Flash Point ]:
284.7±30.1 °C
[ Exact Mass ]:
379.136841
[ LogP ]:
3.82
[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C
[ Index of Refraction ]:
1.589
[ Storage condition ]:
-20℃