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2'-O-Propargyladenosine

Names

[ CAS No. ]:
151390-97-5

[ Name ]:
2'-O-Propargyladenosine

[Synonym ]:
2'-O-propargyl-adenosine
2'-O-propargyladenosine
2'-O-propargyl adenosine
2'-O-(1-propyn-3-yl)adenosine

Biological Activity

[Description]:

2’-O-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H15N5O4

[ Molecular Weight ]:
305.29

[ Exact Mass ]:
305.11200

[ PSA ]:
128.54000

Related Compounds