Duocarmycin MB

Names

[ Name ]:
Duocarmycin MB

Biological Activity

[Description]:

Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MB can be used against multi-drug resistant cell lines.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA Alkylator/Crosslinker

[References]

[1]. Searcey M. Duocarmycins--natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₆ClN₃O₄

[ Molecular Weight ]:
491.97

Duocarmycin MB

Names

Biological Activity

Chemical & Physical Properties

Related Compounds