N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite

Names

[ Name ]:
N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite

[Synonym ]:
Diisopropyl-phosphoramidous acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-fluoro-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

Biological Activity

[Description]:

2'-F-Bz-dC Phosphoramidite can be used in the synthesis of oligoribonucleotides[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Reif B, et, al. Structural Comparison of Oligoribonucleotides and Their 2′-Deoxy-2′-fluoro Analogs by heteronuclear NMR spectroscopy. Helvetica Chimica Acta. 1997 Jou; 80(6): 1952-1971.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₅₁FN₅O₈P

[ Molecular Weight ]:
851.89800

[ Exact Mass ]:
851.34600

[ PSA ]:
159.99000

[ LogP ]:
8.49118

[ Storage condition ]:
2-8℃