KPT-9274
Names
[ CAS No. ]:
1643913-93-2
[ Name ]:
KPT-9274
[Synonym ]:
2-Propenamide, 3-(6-amino-3-pyridinyl)-N-[[5-[4-[(4,4-difluoro-1-piperidinyl)carbonyl]phenyl]-7-(4-fluorophenyl)-2-benzofuranyl]methyl]-, (2E)-
(2E)-3-(6-Amino-3-pyridinyl)-N-{[5-{4-[(4,4-difluoro-1-piperidinyl)carbonyl]phenyl}-7-(4-fluorophenyl)-1-benzofuran-2-yl]methyl}acrylamide
PAK4-IN-1
KPT-9274
Biological Activity
[Description]:
[Related Catalog]:
[Target]
PAK4:100 nM (IC50)
Nampt:120 nM (IC50)
[In Vitro]
[In Vivo]
[Kinase Assay]
[Cell Assay]
[Animal admin]
[References]
[1]. WO2015003166A1
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
857.5±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C35H29F3N4O3
[ Molecular Weight ]:
610.625
[ Flash Point ]:
472.4±34.3 °C
[ Exact Mass ]:
610.219177
[ LogP ]:
4.74
[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C
[ Index of Refraction ]:
1.677
[ Storage condition ]:
-20℃