2’-Deoxy-N6-cyclopentyladenosine

Names

[ CAS No. ]:
170711-45-2

[ Name ]:
2’-Deoxy-N6-cyclopentyladenosine

[Synonym ]:
Adenosine,N-cyclopentyl-2'-deoxy

Biological Activity

[Description]:

2’-Deoxy-N6-cyclopentyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H21N5O3

[ Molecular Weight ]:
319.36

[ Exact Mass ]:
319.16400

[ PSA ]:
105.32000

[ LogP ]:
0.89450