Pyraclostrobine

Names

[ Name ]:
Pyraclostrobine

[Synonym ]:
Carbamic acid, N-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]-N-methoxy-, methyl ester
methyl N-[2-[[1-(4-chlorophenyl)pyrazol-3-yl]oxymethyl]phenyl]-N-methoxycarbamate
methyl 2-[1-(4-chlorophenyl)pyrazol-3-yloxymethyl]-N-methoxycarbanilate
carbamic acid, [2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]methoxy-, methyl ester
Pyraclostrobine
Methyl (2-(((1-(4-chlorophenyl)-1H-pyrazol-3-yl)oxy)methyl)phenyl)(methoxy)carbamate
Pyraclostrobin
methyl N-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]-N-methoxycarbamate
Methyl [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamate

Biological Activity

[Description]:

Pyraclostrobin is a strobilurin fungicide that inhibits mitochondrial complex III of fungal and mammalian cells. Pyraclostrobin induces triglyceride accumulation and triglyceride accumulation in 3T3-L1 cells.

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

Research Areas >> Metabolic Disease

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Anthony L Luz,et al. The High-Production Volume Fungicide Pyraclostrobin Induces Triglyceride Accumulation Associated With Mitochondrial Dysfunction, and Promotes Adipocyte Differentiation Independent of PPARγ Activation, in 3T3-L1 Cells. 2018 Jan 15;393:150-159.

[2]. Alexander H Tuttle, et al.Choice of Vehicle Affects Pyraclostrobin Toxicity in Mice.Chemosphere. 2019 Mar;218:501-506.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
501.1±60.0 °C at 760 mmHg

[ Melting Point ]:
63.7-65.2°

[ Molecular Formula ]:
C₁₉H₁₈ClN₃O₄

[ Molecular Weight ]:
387.817

[ Flash Point ]:
256.8±32.9 °C

[ Exact Mass ]:
387.098572

[ PSA ]:
65.82000

[ LogP ]:
4.25

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.592

[ Storage condition ]:
0-6°C

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H331-H410

[ Precautionary Statements ]:
P261-P273-P304 + P340 + P312-P391-P403 + P233-P501

[ Personal Protective Equipment ]:
Gloves

[ Hazard Codes ]:
N

[ Risk Phrases ]:
50/53

[ Safety Phrases ]:
60-61

[ RIDADR ]:
UN 3077 9/PG 3

[ WGK Germany ]:
2.0

[ RTECS ]:
EZ3441000

[ Hazard Class ]:
9.0

Precursor & DownStream

Precursor

DownStream

Articles

Off-line coupling of multidimensional immunoaffinity chromatography and ion mobility spectrometry: A promising partnership.

J. Chromatogr. A. 1426 , 110-7, (2015)

The extreme specificity of immunoaffinity chromatography (IAC) columns coupled to the high sensitivity of ion mobility spectrometry (IMS) measurements makes this combination really useful for rapid, s...