5’-O-DMTr-2’-OMeU-methyl phosphonamidite

Names

[ CAS No. ]:
191786-64-8

[ Name ]:
5’-O-DMTr-2’-OMeU-methyl phosphonamidite

Biological Activity

[Description]:

5’-O-DMTr-2’-OMeU-methyl phosphonamidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₈H₄₈N₃O₈P

[ Molecular Weight ]:
705.78