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2′-Deoxy-5-methylisocytidine

Names

[ CAS No. ]:
19316-88-2

[ Name ]:
2′-Deoxy-5-methylisocytidine

[Synonym ]:
2'-Decxy-5-methylisocytidine
5-Methyl-2'-deoxyisouridine
5-METHYL-2'-DEOXYISOCYTIDINE

Biological Activity

[Description]:

2′-Deoxy-5-methylisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H16N2O4

[ Molecular Weight ]:
240.26

[ Exact Mass ]:
241.10600

[ PSA ]:
110.60000


Related Compounds