1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine

Names

[ CAS No. ]:
206055-67-6

[ Name ]:
1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine

[Synonym ]:
5-methyl-2'-O,4'-C-methyleneuridine
1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)thymine
(1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-3-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane
(1S,3R,4R,7S)-7-hydroxy-1-hydroxymethyl-(thymin-1-yl)-2,5-dioxabicyclo[2.2.1]heptane
2'-O,4'-C-methylenethymidine
2'-O,4'-C-methylene-5-methyluridine

Biological Activity

[Description]:

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Sharma VK, et al. Chemoenzymatic convergent synthesis of 2'-O,4'-C-methyleneribonucleosides. J Org Chem. 2014 Jul 3;79(13):6336-41.

Chemical & Physical Properties

[ Density]:
1.598

[ Molecular Formula ]:
C11H14N2O6

[ Molecular Weight ]:
270.23900

[ Exact Mass ]:
270.08500

[ PSA ]:
113.78000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds