2-Aminoadenosine

Names

[ CAS No. ]:
2096-10-8

[ Name ]:
2-Aminoadenosine

[Synonym ]:
Aminoadenosine
2,6-DiaMinopurinosine
9-Pentofuranosyl-9H-purine-2,6-diamine
2-AMINO-ADENOSINE
2,6-DIAMINOPURINE RIBOSIDE
(2R,3R,4S,5R)-2-(2,6-Diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydro-3,4-furandiol
2-Amino-adenoside
2-AMINE ADENOSINE
2,6-Diamino-9-(β-D-ribofuranosyl)purine
MFCD00053556
2-Aminoadenosine
9H-Purine-2,6-diamine, 9-β-D-ribofuranosyl-
2,6-Diamino-9-(beta-D-ribofuranosyl)purine
9-(β-D-Ribofuranosyl)-9H-purin-2,6-diamin
EINECS 209-610-8
Adenosine, 2-amino-
2,6-DiaMinonebularine
9H-Purine-2,6-diamine, 9-pentofuranosyl-
2-AMinoadenosin
purine-2,6-diamine ribonucleoside
2-NH2-A
2,6-DIAMINOPURINE-RIBOSIDE

Biological Activity

[Description]:

2-Aminoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
2.3±0.1 g/cm3

[ Boiling Point ]:
798.5±70.0 °C at 760 mmHg

[ Melting Point ]:
241-243°C (dec.)

[ Molecular Formula ]:
C₁₀H₁₄N₆O₄

[ Molecular Weight ]:
282.26

[ Flash Point ]:
436.7±35.7 °C

[ Exact Mass ]:
282.107666

[ PSA ]:
165.56000

[ LogP ]:
-1.08

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.986

[ Storage condition ]:
2~8℃

MSDS

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Safety Information

[ HS Code ]:
2942000000

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2942000000