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5-carboxymethyluridine

Names

[ CAS No. ]:
20964-06-1

[ Name ]:
5-carboxymethyluridine

[Synonym ]:
2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetic acid
5-Carboxymethyluridine

Biological Activity

[Description]:

5-Carboxymethyluridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H14N2O8

[ Molecular Weight ]:
302.24

[ Exact Mass ]:
302.07500

[ PSA ]:
162.34000


Related Compounds