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USP7-IN-5

Names

[ CAS No. ]:
2166599-74-0

[ Name ]:
USP7-IN-5

Biological Activity

[Description]:

USP7-IN-5 is a potent ubiquitin specific protease 7 (USP7) inhibitor extracted from patent WO2017212012A1, example 40, has an IC50 of 49.9 nM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[Target]

IC50: 49.9 nM (USP7)[1]


[In Vitro]

USP7-IN-5 (example 40) shows cytotoxicity to MM1S cells, with an IC50 31.5 nM[1].

[References]

[1]. András Kotschy, et al. New piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them. WO2017212012A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H43N5O6

[ Molecular Weight ]:
641.76

Related Compounds