CDK1-IN-2

Names

[ CAS No. ]:
220749-41-7

[ Name ]:
CDK1-IN-2

[Synonym ]:
2H-Indol-2-one, 3-[(2-chloro-1H-indol-3-yl)methylene]-1,3-dihydro-, (3E)-
(3E)-3-[(2-Chloro-1H-indol-3-yl)methylene]-1,3-dihydro-2H-indol-2-one
(3E)-3-[(2-chloro-1H-indol-3-yl)methylidene]-1,3-dihydro-2H-indol-2-one
Cdk1 Inhibitor

Biological Activity

[Description]:

CDK1-IN-2 is a CDK1 inhibitor (IC50: 5.8 μM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK1:5.8 μM (IC50)

[In Vitro]

CDK1-IN-2 (“CDK1 inhibitor 1”, 0-19.8 μM, 24 h) arrests HCT-116 cells in G2/M phase[1].

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
585.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₁ClN₂O

[ Molecular Weight ]:
294.735

[ Flash Point ]:
307.7±30.1 °C

[ Exact Mass ]:
294.056000

[ LogP ]:
4.02

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.778

[ Storage condition ]:
2-8°C

CDK1-IN-2

Names

Biological Activity

Chemical & Physical Properties

Related Compounds