<Suppliers Price>

Riddelline

Names

[ CAS No. ]:
23246-96-0

[ Name ]:
Riddelline

[Synonym ]:
13,19-Didehydro-12,18-dihydroxysenecionan-11,16-dione
Riddeline
Riddelliine
Riddeliine
12,18-dihydroxy-senecion-13(19)-ene-11,16-dione
Riddeliin
(15Z)-12,18-dihydroxy-13,19-didehydrosenecionan-11,16-dione
Riddelline

Biological Activity

[Description]:

Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Research Areas >> Others

[References]

[1]. J C Mirsalis, et al. In Vivo Measurement of Unscheduled DNA Synthesis and S-phase Synthesis as an Indicator of Hepatocarcinogenesis in Rodents. 5.097Q1 Cell Biol Toxicol. 1987 Jun;3(2):165-73.

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
593.2ºC at 760 mmHg

[ Molecular Formula ]:
C18H23NO6

[ Molecular Weight ]:
349.37800

[ Flash Point ]:
312.5ºC

[ Exact Mass ]:
349.15300

[ PSA ]:
96.30000

[ LogP ]:
0.02320

[ Vapour Pressure ]:
1.53E-16mmHg at 25°C

[ Index of Refraction ]:
1.601

Safety Information

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Related Compounds