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Kolavenic acid analog

Names

[ CAS No. ]:
2379777-37-2

[ Name ]:
Kolavenic acid analog

Biological Activity

[Description]:

Kolavenic acid analog (KAA) is an anticancer agent. Kolavenic acid analog shows strong activity against HSET-overproducing yeast cells. Kolavenic acid analog inhibits centrosome clustering in human cancer cells containing high HSET levels and supernumerary centrosomes[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Kinesin
Signaling Pathways >> Cytoskeleton >> Kinesin

[References]

[1]. Kurisawa N, et al. Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cells. Bioorg Med Chem. 2020 Jan 1;28(1):115154.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H38O4

[ Molecular Weight ]:
402.57

Related Compounds