Germacrene D

Names

[ Name ]:
Germacrene D

[Synonym ]:
(-)-(7S)-germacrene D
(8S,1E,6E)-1-methyl-5-methylene-8-(1-methylethyl)-1,6-cyclodecadiene
(S)-germacrene D
(+)-germacrene-D

Biological Activity

[Description]:

Germacrene D is isolated from Bursera species. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> Fungal

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: bacterial[1]

[In Vitro]

Germacrene D shows antibacterial and antifungal activities, the mechanism of antimicrobial action of it may be related to permeabilization of the cells and disruption of the membrane integrity[1].

[References]

[1]. Noge K, et al. Germacrene D, a common sesquiterpene in the genus Bursera (Burseraceae).Molecules. 2009 Dec 15;14(12):5289-97.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₄

[ Molecular Weight ]:
204.35100

[ Exact Mass ]:
204.18800

[ LogP ]:
4.89130

[ Vapour Pressure ]:
0.00673mmHg at 25°C

Safety Information

[ HS Code ]:
2902199090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2902199090

[ Summary ]:
2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%