FT709

Names

[ Name ]:
FT709

Biological Activity

[Description]:

FT709 is a potent and selective USP9X inhibitor, an IC50 of 82 nM. USP9X has been linked with centrosome function, chromosome alignment during mitosis, EGF receptor degradation, chemo-sensitization, and circadian rhythms[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Deubiquitinase

[References]

[1]. Clancy A, et, al. The deubiquitylase USP9X controls ribosomal stalling. J Cell Biol. 2021 Mar 1;220(3):e202004211.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂N₄O₇S

[ Molecular Weight ]:
498.51