1-Benzoyl-2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazine

Names

[ Name ]:
1-Benzoyl-2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazine

[Synonym ]:
EINECS 263-849-5
Benzoic acid, 2-[[trans-4-[[[[2-nitro-4-(trifluoromethyl)phenyl]sulfonyl]amino]methyl]cyclohexyl]carbonyl]hydrazide
N-({trans-4-[(2-Benzoylhydrazino)carbonyl]cyclohexyl}methyl)-2-nitro-4-(trifluoromethyl)benzenesulfonamide

Biological Activity

[Description]:

S 25585 is a potent and selective neuropeptide Y (NPY) Y5 receptor antagonist. S 25585 reduces food intake but not through blockade of the NPY Y5 receptor[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Neuropeptide Y Receptor

[References]

[1]. Della-Zuana O, et al. A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor. Int J Obes Relat Metab Disord. 2004 Apr;28(4):628-39.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₂H₂₃F₃N₄O₆S

[ Molecular Weight ]:
528.501

[ Exact Mass ]:
528.129028

[ LogP ]:
3.80

[ Index of Refraction ]:
1.563