CDK7/12-IN-1

Names

[ CAS No. ]:
2654075-94-0

[ Name ]:
CDK7/12-IN-1

Biological Activity

[Description]:

CDK7/12-IN-1 is a selective CDK7/12 inhibitor with IC50s of 3 and 277 nM for CDK7 and CDK 12, respectively. CDK7 and CDK12 inhibition is an effective strategy to inhibit tumour growth[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[References]

[1]. Edward AINSCOW, et al. 4-[[(7-aminopyrazolo[1,5-a]pyrimidin-5-yl)amino]methyl]piperidin-3-ol compounds and their therapeutic use. WO2021122745A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C25H34N8O

[ Molecular Weight ]:
462.59

Related Compounds