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N6-Furfuryl-2-aminoadenosine

Names

[ CAS No. ]:
26783-39-1

[ Name ]:
N6-Furfuryl-2-aminoadenosine

[Synonym ]:
(2R,3R,4S,5R)-2-{2-Amino-6-[(furan-2-ylmethyl)-amino]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Biological Activity

[Description]:

N6-Furfuryl-2-aminoadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H18N6O5

[ Molecular Weight ]:
362.34

[ Exact Mass ]:
362.13400

[ PSA ]:
164.71000

Related Compounds