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SDH-IN-1

Names

[ CAS No. ]:
2685795-52-0

[ Name ]:
SDH-IN-1

Biological Activity

[Description]:

SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Zihui Yang, et al. Design, Synthesis, and Antifungal Activity of Novel Thiophene/Furan-1,3,4-Oxadiazole Carboxamides as Potent Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2021 Nov 17;69(45):13373-13385.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H9Cl2N3O2S

[ Molecular Weight ]:
354.21

Related Compounds