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DNA-PK-IN-4

Names

[ CAS No. ]:
2722645-10-3

[ Name ]:
DNA-PK-IN-4

Biological Activity

[Description]:

DNA-PK-IN-4 is a potent inhibitor of DNA-PK. DNA-PK-IN-4 is a imidazolinone derivative compound. DNA-PK-IN-4 inhibits DNA-PKcs activity, thus greatly reducing tumor DNA repair and inducing cells to enter the apoptotic program. DNA-PK-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021209055A1, compound 27)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> DNA-PK
Signaling Pathways >> PI3K/Akt/mTOR >> DNA-PK

[References]

[1]. Yonggang Wei, et al. Imidazolinone derivatives and their applications in medicine. Patent WO2021209055A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H24N6O3

[ Molecular Weight ]:
396.44


Related Compounds