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SB-216

Names

[ CAS No. ]:
2756818-39-8

[ Name ]:
SB-216

Biological Activity

[Description]:

SB-216 is a potent tubulin polymerization inhibitor. SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer.  SB-216 can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[Target]

IC50: tubulin polymerization[1]


[References]

[1]. Souvik Banerjee, et al. X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor. J Med Chem

Chemical & Physical Properties

[ Molecular Formula ]:
C17H18N4O2

[ Molecular Weight ]:
310.35

Related Compounds