Uridine-5-oxyacetic acid

Names

[ CAS No. ]:
28144-25-4

[ Name ]:
Uridine-5-oxyacetic acid

[Synonym ]:
o(5)u
2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]oxyacetic acid
Uridine-5-oxyacetic acid
5-(carboxymethoxy)uridine

Biological Activity

[Description]:

Uridine-5-oxyacetic acid is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C11H14N2O9

[ Molecular Weight ]:
318.24

[ Exact Mass ]:
318.07000

[ PSA ]:
171.57000

Related Compounds