2-Methylamino-N6-methyladenosine

Names

[ CAS No. ]:
28360-91-0

[ Name ]:
2-Methylamino-N6-methyladenosine

[Synonym ]:
N-Methyl-2-(methylamino)adenosine
Adenosine, N-methyl-2-(methylamino)-

Biological Activity

[Description]:

2-Methylamino-N6-methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
697.9±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C12H18N6O4

[ Molecular Weight ]:
310.31

[ Flash Point ]:
375.9±34.3 °C

[ Exact Mass ]:
310.138947

[ LogP ]:
-1.73

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.797

Related Compounds