OXi8007

Names

[ Name ]:
OXi8007

[Synonym ]:
Disodium 2-methoxy-5-[6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indol-2-yl]phenyl phosphate
Methanone, [6-methoxy-2-[4-methoxy-3-(phosphonooxy)phenyl]-1H-indol-3-yl](3,4,5-trimethoxyphenyl)-, sodium salt (1:2)

Biological Activity

[Description]:

OXi8007 is a water-soluble phosphate prodrug of OXi8006, a tubulin-binding compound.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin

Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin

[References]

[1]. Strecker TE, et al. The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts. Cancer Lett. 2015 Dec 1;369(1):229-41.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₄NNa₂O₁₀P

[ Molecular Weight ]:
587.423

[ Exact Mass ]:
587.093323