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(+)-Phomalactone

Names

[ CAS No. ]:
28921-94-0

[ Name ]:
(+)-Phomalactone

[Synonym ]:
2H-Pyran-2-one,5,6-dihydro-5-hydroxy-6-(1E)-1-propenyl-,(5S,6S)
phomalacton
5,6-dihydro-5-hydroxy-6-prop-2-enyl-2H-pyran-2-one
[5S,6S,(+)]-5,6-Dihydro-5-hydroxy-6-[(E)-1-propenyl]-2H-pyran-2-one
(+)-phomalactone

Biological Activity

[Description]:

Phomalactone, produced by the fungus Nigrospora sphaerica, specifically inhibits the mycelial growth of Phytophthora infestans, with an MIC value of 2.5 mg/L[1]. Phomalactone is phytotoxic to Z. elegans and other plant species by inhibition of seedling growth and by causing electrolyte leakage from photosynthetic tissues of both Z. elegans leaves and cucumber cotyledons[2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Kim JC, et al. Activity against plant pathogenic fungi of phomalactone isolated from Nigrospora sphaerica. Pest Manag Sci. 2001;57(6):554-559.

[2]. Meepagala KM, et al. Phomalactone from a Phytopathogenic Fungus Infecting ZINNIA elegans (ASTERACEAE) Leaves. J Chem Ecol. 2015;41(7):602-612.

Chemical & Physical Properties

[ Density]:
1.155g/cm3

[ Boiling Point ]:
329.2ºC at 760mmHg

[ Molecular Formula ]:
C8H10O3

[ Molecular Weight ]:
154.16300

[ Flash Point ]:
151ºC

[ Exact Mass ]:
154.06300

[ PSA ]:
46.53000

[ LogP ]:
0.40500

[ Vapour Pressure ]:
0.000105mmHg at 25°C

[ Index of Refraction ]:
1.611

Related Compounds