Adenosine,8-(methylthio)- (7CI,8CI,9CI)

Names

[ Name ]:
Adenosine,8-(methylthio)- (7CI,8CI,9CI)

[Synonym ]:
8-Methylmercapto-adenosin
8-methylsulfanyl-adenosine
8-MeS-adenosine
1,3-dimethyl-8-(methylsulfonyl)-3,7-dihydro-1h-purine-2,6-dione
8-(methylthio)adenosine
8-methanesulfonyl-1,3-dimethyl-3,7(9)-dihydro-purine-2,6-dione
8-Methylsulfonyl-theophyllin

Biological Activity

[Description]:

8-Methylthio-adenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Density]:
1.98g/cm3

[ Boiling Point ]:
704.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₅O₄S

[ Molecular Weight ]:
313.33

[ Flash Point ]:
379.8ºC

[ Exact Mass ]:
313.08400

[ PSA ]:
164.84000

[ Vapour Pressure ]:
7.93E-21mmHg at 25°C

[ Index of Refraction ]:
1.878

Adenosine,8-(methylthio)- (7CI,8CI,9CI)

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds