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9H-Purin-6-amine,9-(6-deoxy-b-D-allofuranosyl)-

Names

[ CAS No. ]:
3253-81-4

[ Name ]:
9H-Purin-6-amine,9-(6-deoxy-b-D-allofuranosyl)-

Biological Activity

[Description]:

5’(R)-C-Methyladenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H17N5O4

[ Molecular Weight ]:
295.29

[ Exact Mass ]:
281.11200

[ PSA ]:
139.54000

Related Compounds