L67
Names
[ CAS No. ]:
325970-71-6
[ Name ]:
L67
[Synonym ]:
2-[(3,5-Dibromo-4-methylphenyl)amino]-N'-[(E)-(2-hydroxy-5-nitrophenyl)methylene]acetohydrazide
L67
Biological Activity
[Description]:
L67 is a novel, competitive human DNA ligase inhibitor, inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.IC50 value: 10 μM [1]Target: DNA ligasesin vitro: L67 significantly increases the cytotoxicity of DNA damaging agents.[1] L67 also inhibits cell proliferation. [2]
[Related Catalog]:
[References]
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Adenine
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Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Molecular Formula ]:
C16H14Br2N4O4
[ Molecular Weight ]:
486.115
[ Exact Mass ]:
483.938171
[ LogP ]:
6.23
[ Index of Refraction ]:
1.681
[ Storage condition ]:
2-8℃