A-315675

Names

[ CAS No. ]:
335679-69-1

[ Name ]:
A-315675

[Synonym ]:
D-Proline,5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-(1Z)-1-propenyl-,(4S,5R)
(5R)-((1R)-acetylamino-(2S)-methoxy-(2S)-methylpentyl)-(4S)-Z-propenylpyrrolidine-(2R)-carboxylic acid
5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-[(1Z)-1-propenyl]-(4S,5R)-D-proline
(-)-(2R,4S,5R)-5-[(1R,2S)-1-(acetylamino)-2-methoxy-2-methylpentyl]-4-[(1Z)-prop-1-enyl]pyrrolidine-2-carboxylic acid
5-[(2S,1R)-1-(Acetylamino)-2-methoxy-2-methylpentyl](4S,2R)-4-(prop-1-enyl)pyrrolidine-2-carboxylic acid
(+-)-(2R,3S,5R,1'R,2'S)-2-(1-Acetamido-2-methyl-2-methoxy)pentyl-3-(cis-propen-1-yl)-pyrrolidine-5-carboxylic Acid

Biological Activity

[Description]:

A-315675 is a potent highly potent inhibitor of A and B strain influenza virus neuraminidases inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Inflammation/Immunology

[References]

[1]. Warren M Kati, et al. In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication. Antimicrob Agents Chemother. 2002 Apr;46(4):1014-21.  

Chemical & Physical Properties

[ Density]:
1.101g/cm3

[ Boiling Point ]:
520.9ºC at 760 mmHg

[ Molecular Formula ]:
C17H30N2O4

[ Molecular Weight ]:
326.43100

[ Flash Point ]:
268.8ºC

[ Exact Mass ]:
326.22100

[ PSA ]:
91.15000

[ LogP ]:
2.87280

[ Index of Refraction ]:
1.523

Synthetic Route

Click to get detail synthetic route