N,N-Dimethyl-2’-O-methylcytidine

Names

[ CAS No. ]:
34218-81-0

[ Name ]:
N,N-Dimethyl-2’-O-methylcytidine

[Synonym ]:
Nno-tmc
Cytidine,N,N-dimethyl-2'-O-methyl

Biological Activity

[Description]:

N,N-Dimethyl-2’-O-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H19N3O5

[ Molecular Weight ]:
285.30

[ Exact Mass ]:
285.13200

[ PSA ]:
97.05000

Related Compounds