3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

Names

[ Name ]:
3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

[Synonym ]:
3'-Chloro-3'-deoxy-5'-O-(triphenylmethyl)thymidine
3'-Chloro-3'-deoxy-5'-O-tritylthymidine
3'-chloro-O5'-trityl-3'-deoxy-thymidine
3'-Chlor-3'-desoxy-5'-O-tritylthymidin
5'-O-trityl-3'-chlorothymidine

Biological Activity

[Description]:

3′-Chloro-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₇ClN₂O₄

[ Molecular Weight ]:
502.99

[ Exact Mass ]:
502.16600

[ PSA ]:
73.58000

[ LogP ]:
5.16090

3'-CHLORO-3'-DEOXY-5'-O-TRITYLTHYMIDINE

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds