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Casein kinase 1δ-IN-3

Names

[ CAS No. ]:
349438-77-3

[ Name ]:
Casein kinase 1δ-IN-3

[Synonym ]:
MFCD02862179
2-(2-Methoxyphenyl)-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide
Benzeneacetamide, 2-methoxy-N-(6-methyl-2-benzothiazolyl)-

Biological Activity

[Description]:

Casein kinase 1δ-IN-3 (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase
Research Areas >> Neurological Disease
Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase

[Target]

CKIδ:6.5376 M (pIC50)


[References]

[1]. Makhuri FR, et al. Computer-aided scaffold hopping to identify a novel series of casein kinase 1 delta (CK1d) inhibitors for amyotrophic lateral sclerosis. Eur J Pharm Sci. 2015 Oct 12;78:151-62.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C17H16N2O2S

[ Molecular Weight ]:
312.38614

[ Exact Mass ]:
312.093262

[ LogP ]:
3.99

[ Index of Refraction ]:
1.680

Related Compounds