S26948

Names

[ Name ]:
S26948

[Synonym ]:
dimethyl 2-{4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3(2H)-yl)ethoxy]benzyl}-malonate

Biological Activity

[Description]:

S26948 is a specific peroxisome proliferator-activated receptor γ (PPARγ) modulator (EC50=8.83 nM) with potent antidiabetes and antiatherogenic effects. S26948 is a specific high-affinity agonist for PPARγ[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Research Areas >> Metabolic Disease

[References]

[1]. Maria Carmen Carmona, et al. S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects. Diabetes. 2007 Nov;56(11):2797-808.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₂₅NO₇S

[ Molecular Weight ]:
519.56600

[ Exact Mass ]:
519.13500

[ PSA ]:
129.14000

[ LogP ]:
3.87770

MSDS

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Safety Information

[ RIDADR ]:
NONH for all modes of transport

S26948

Names

Biological Activity

Chemical & Physical Properties

MSDS

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Safety Information

Synthetic Route

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Precursor & DownStream

Precursor

DownStream