2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

[ Name ]:
2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

[Synonym ]:
8-methoxyacenaphthen-1-one
8-Methoxyadenosine
8-Methoxy-acenaphthen-1-on
8-Methoxyadenosin

Biological Activity

[Description]:

8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅N₅O₅

[ Molecular Weight ]:
297.27

[ Exact Mass ]:
297.10700

[ PSA ]:
148.77000

2-(6-amino-8-methoxy-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds