a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-

Names

[ Name ]:
a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-

Biological Activity

[Description]:

3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.123g/cm3

[ Boiling Point ]:
291ºC at 760mmHg

[ Molecular Formula ]:
C₁₂H₂₀O₅

[ Molecular Weight ]:
244.28

[ Flash Point ]:
112ºC

[ Exact Mass ]:
244.13100

[ PSA ]:
46.15000

[ LogP ]:
1.40440

[ Index of Refraction ]:
1.461

a-D-ribo-Hexofuranose,3-deoxy-1,2:5,6-bis-O-(1-methylethylidene)-

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds