2',3'-Dideoxy-3'-fluorocytidine

Names

[ Name ]:
2',3'-Dideoxy-3'-fluorocytidine

[Synonym ]:
Cytidine, 2',3'-dideoxy-3'-fluoro-
2',3'-Dideoxy-3'-fluorocytidine
2'-deoxy-3'-fluoro-d-cytidine

Biological Activity

[Description]:

2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
418.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₂FN₃O₃

[ Molecular Weight ]:
229.21

[ Flash Point ]:
206.6±31.5 °C

[ Exact Mass ]:
229.086273

[ PSA ]:
90.37000

[ LogP ]:
-1.07

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.665

2',3'-Dideoxy-3'-fluorocytidine

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds