Adenosine-13C

Names

[ CAS No. ]:
54447-57-3

[ Name ]:
Adenosine-13C

[Synonym ]:
Adenosine-5'-13C
Adenosine-5' 13C

Biological Activity

[Description]:

Adenosine-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology,

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K. Pharmacology of Adenosine Receptors: The State of the Art. Physiol Rev. 2018;98(3):1591-1625.;Fredholm BB. Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13N5O4

[ Molecular Weight ]:
268.23400

[ Exact Mass ]:
268.10000

[ PSA ]:
139.54000

Related Compounds