<Suppliers Price>

Nepetoidin B

Names

[ CAS No. ]:
55486-06-1

[ Name ]:
Nepetoidin B

[Synonym ]:
(Z)-2-(3,4-Dihydroxyphenyl)vinyl (2E)-3-(3,4-dihydroxyphenyl)acrylate
2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, (Z)-2-(3,4-dihydroxyphenyl)ethenyl ester, (2E)-

Biological Activity

[Description]:

Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

NF-κB, bacterial, fungal[1][2].


[References]

[1]. Kim M, et al. Nepetoidin B from Salvia plebeia R. Br. Inhibits Inflammation by Modulating the NF-κB and Nrf2/HO-1 Signaling Pathways in Macrophage Cells. Antioxidants (Basel). 2021 Jul 28;10(8):1208.  

[2]. Wu X, et al. Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways. Phytother Res. 2017 Jul;31(7):1072-1077.  

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
587.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H14O6

[ Molecular Weight ]:
314.29

[ Flash Point ]:
219.4±23.6 °C

[ Exact Mass ]:
314.079041

[ LogP ]:
2.67

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.752

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds