Thymidine, a-azido- (9CI)

Names

[ Name ]:
Thymidine, a-azido- (9CI)

[Synonym ]:
5-azido-2'-O-deoxythymidine
5-azidomethyl-2'-deoxyuridine

Biological Activity

[Description]:

α-Azidothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₃N₅O₅

[ Molecular Weight ]:
283.24

[ Exact Mass ]:
283.09200

[ PSA ]:
154.30000

Thymidine, a-azido- (9CI)

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds