AZD5438
Names
[ CAS No. ]:
602306-29-6
[ Name ]:
AZD5438
[Synonym ]:
4-(1-Isopropyl-2-methyl-1H-imidazol-5-yl)-N-[4-(methylsulfonyl)phenyl]pyrimidin-2-amine
AZD 5438
4-(1-Isopropyl-2-methyl-1H-imidazol-5-yl)-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine
S2621_Selleck
2-Pyrimidinamine, 4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-
AZD-5438,AZD5438
AZD5438
AZD-5438
Biological Activity
[Description]:
[Related Catalog]:
[Target]
cdk2-cyclin E:6 nM (IC50)
cdk2-cyclin A:45 nM (IC50)
cdk5-p25:14 nM (IC50)
cdk1-cyclin B1:16 nM (IC50)
cdk9-cyclin T:20 nM (IC50)
cdk6-cyclin D3:21 nM (IC50)
cdk4-cyclin D1:449 nM (IC50)
cdk7-cyclin H:821 nM (IC50)
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
655.2±65.0 °C at 760 mmHg
[ Molecular Formula ]:
C18H21N5O2S
[ Molecular Weight ]:
371.457
[ Flash Point ]:
350.1±34.3 °C
[ Exact Mass ]:
371.141602
[ PSA ]:
98.15000
[ LogP ]:
2.13
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.648
[ Storage condition ]:
Desiccate at RT
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%